Which application/end-user or product type may seek incremental growth prospects? AAV6 binding appears to be less affected by neuraminidase compared with AAV1 binding, suggesting that AAV6 may also bind to…
Background was washed out with deionized water and gel was scanned with the default instrument settings for analysis (Lexmark CX727 scanner). Inhibition of glycolipid synthesis was carried out as described…
Match up the necessities of your chemical technicians with listings on our marketplace, and stock up to ensure all of your reactions are lined. Sometimes chemical processes are only as…
Treatment of isolated-perfused lungs with neuraminidase from Vibrio cholerae leads to pulmonary edema. A third key observation in our study is the pattern of alveolar edema observed when isolated-perfused lungs…
Preliminary studies have demonstrated structural differences in the glycocalyx of pulmonary artery endothelial cells compared with pulmonary microvascular endothelial cells. In addition, if the interaction between sialic acid and the…
This was followed by the addition of neuraminidase solution or buffer control to each well and continued resistance measurement 4 (or more) h. AAV6 relies more on sialic acid or…
Briefly, polySia avDP20 was oxidized to an aldehyde by sodium metaperiodate, and then hydrazide coupled biotin (Thermo Scientific) was conjugated to form a hydrazone bond. AAV6 and newly identified type…
Different AAV serotypes display distinct tissue tropism, believed to be related to the distribution of their receptors on target cells. The AAV serotype helper plasmids pXR1, pXR2, pXR4, and pXR5,…
ΔOD595 for triplicate experiments is shown: ΔnanT (A) and ΔyjhB (B). ΔOD595 for triplicate experiments is shown: BW25113 (B), ΔyjhC (C), and complemented yjhC (D). If you have any inquiries…
The data from these assays were complemented by a glycan array analysis which determined that AAV1 efficiently binds to NeuAcα2-3GalNAcβ1-4GlcNAc as well as glycoproteins containing NeuAcα2-3/α2-6Galβ1-4GlcNAc N-linked glycans. If you…
